No Mutants Allowed seemingly closes its Fallout 10th anniversary celebrations with a Fallout 2 post-release interview. The interview is originally from Desslock's Gamespot site, and now re-released here.
Desslock: What's next for the Fallout series, assuming the game is at least as successful as the original game? Don't worry, we won't hold you to anything
Feargus Urquhart: We are kicking around ideas for Fallout 3. Nothing official yet, but we are thinking of making it using a 3D engine. I don't want people to panic here, because it is not going to be a 1st person shooter. We are just going to use the 3D engine to display an isometric world in 3D. So people will still play the game much the same way as they are doing now in Fallout 1 and 2.