BioShock PC Blowout

2K Games' official Cult of Rapture website has been updated with new details about the Windows version of the game, including a PC-specific podcast, screenshots of the interface, a FAQ, and more. Given the amount of games coming out yet this year, I'm thinking it might be a good time to upgrade:
How much will a single-core processor hold you back in playing this game?

A single core processor will reduce your frame rate compared to an equivalently clocked dual core processor. However the game is still perfectly playable on single-core processors using lower detail settings.