I think some items appear randomly as well each time you play so that you wil always experience having different item combinations to screw around with.
I went through twice (once good, once evil) and I think going through again could become a little tedious *cough* Dragons tooth *cough*

Maybe in a couple of months though?
If this game had the class selection that BG2 has I would play through it almost constantly. Especially considering that you have to create all your party members.
You could have 6 monks or 6 Skalds or 6 Inquisitors or 6....... *continues to rant*