I'd recommend making 2, maybe 3 characters, though. Then play it as a "single-player". The in-game NPCs are a splatload of fun, and you can footle through their quests with a strong core party. Too strong. When doing multiplayer parties, I (and, I expect, everybody else) makes insanely maxed-out characters. A CHA dropped to 3 gives you a whole mess of points to put into STR, DEX, CON...
I played it through with a Cleric/Mage (PC), and a created Half-orc Kensai, and a dual-classed Swashbuckler 10 | Fighter. Crazy powerful by the end of the game. It got quite silly, actually. The Black dragon died in about 3 rounds.
