@karlg:
Im having the exact same problem, the quest won't 'start'.
My journal doesnt get updated or anything, although Aegisfield acknowledges the fact im trying to solve it.
I can't talk to Rampah or Rose either. I did complete the quest eventually (or at least get the XP), because i wanted to move on, maybe not a wise decision, but oh well:
SPOILER (i guess?)
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If u kill Rampah yuo can loot the skin and talk about it with the merchant. Then when u run to the Tanner he won't say anything interesting, neither can you confront him with anything, but when you start attacking him he will talk about his business and runs off downstairs, then follow him, and you'll find out about his evil business etc etc. I did get the Exp. when i reported back to Aegisfield, and my journal got 'updated' with the quest after defeating those Rune Assassins in the basement, but this isnt really how it's supposed to be done, and wasnt very satisfactory either
So, does anyone know if some patch/fix/update/anything solves this? or have i done something wrong?