A mod with 9 new masteries has been released for Titan Quest by Pink Frog the creator.
Vampire, Alchemy, Sorcery, Close Combat, Mysticism, Archery, Bestiary, Chronoscopy, Construction
It is very fun. Look for it on titanquest.net
Here's a link to Pink Frog's website with information on the mastery and a section where you can download the mod including instructions. I am having fun with my Experimenter (Vampire/Alchemist). So far I got my first ever Revenant Plate drop...most auspicious!
Linky:
:: Masteries ... A TitanQuest - Mod ::