Heh, just got it today and got our of bed today after two weeks of sickness - heh double positive
Anyway, it runs fine with 1Gb of RAM, my Radeon 9800 and Athlon 64 3000+ with medium settings. Some small stutters but nothing major.
I haven't played all that much but my first impressions is that combat is very nice indeed. As already mentioned, it sounded a bit complicated at first but actually it isn't. This is the only part that I managed to look into after my initial first time with the game and I admit to liking this more than before.
Can't tell you a thing else right now but in a day or two I should have at least half of my facts straight as I'm still off work and feeling better so I can play