Yeah, first of all note that I don't have the game so I don't know how these feats are implemented. But, wouldn't a rogue with ambidexterity and two handed fighting equiping daggers (which by the way offer less penalties) rock? If you make it human, you can get both feats at the first level. The real beauty is that the next feat you choose would be weapon finesse, so a high dexterity rogue will be really very good. Of course, consider the sneak attack advantage as well.
Of course, after that you can specialise in daggers and get improved two handed fighting...
