The player has successfully invented at least one item.

The player has purchased one slot in any Plasmid or Tonic track.

The player has fully upgraded one weapon.

The player has performed at least one successful hack.

The player has taken at least one photo in every research group.

The player has taken at least one Research Photo of a Splicer.

The player has fully upgraded two weapons.

The player has acquired at least one weapon upgrade.

The player has successfully invented at least 100 items.

The player has successfully completed the Welcome To Rapture Level.

The player has fully upgraded five weapons.

The player has entered Sander Cohen's personal quarters.

The player has fully upgraded four weapons.

The player has fully researched the Bouncer.

The player has fully researched the Leadhead Splicer.

The player has fully researched the Houdini Splicer.

The player has fully researched the Little Sister.

The player has fully researched the Nitro Splicer.

The player has fully researched the Rosie.

The player has fully researched the Spider Splicer.

The player has fully researched the Thuggish Splicer.

The player has successfully hacked a safe.

The player has successfully hacked a security bot.

The player has successfully hacked a security camera.

The player has successfully hacked a turret.

The player has successfully hacked a vending machine.

The player has taken a picture of Sander Cohen's corpse.

The player has hit the jackpot at a slot machine.

The player has fully upgraded three weapons.

The player has shocked an enemy in the water.

The player has defeated the crazed Dr. Steinman.

The player has defeated Peach Wilkins.

The player has restored the forests of Arcadia.

The player has purchased every slot in one of the Plasmid or Tonic tracks.

The player has taken a Research Photo of the highest grade.

The player has maxed out all possible research.

The player has acquired all upgrades for all weapons.

The player has successfully invented all possible ammo types.

The player has become a Big Daddy.

The player has broken Fontaine's mind control.

The player has completed Sander Cohen's great masterpiece.

The player has defeated Andrew Ryan.

The player has either Harvested or Rescued every possible Little Sister.

Complete the game on the hardest difficulty setting.

The player has successfully completed 50 hacks.

The player has found every audio diary.

The player has purchased every slot in all four Plasmid and Tonic tracks.

The player has collected or invented 53 Tonics in the Physical, Engineering and Combat tracks.

Complete the game on Hard difficulty without using a Vita-Chamber.

The player has defeated Atlas.

The player has completed the game without harvesting any Little Sisters.