Successfully complete the Welcome To Rapture Level.

Purchased every slot in one of the Plasmid or Tonic tracks.

Purchased every slot in all four Plasmid and Tonic tracks.

Purchase one slot in any Plasmid or Tonic track.

Acquire at least one weapon upgrade.

Fully upgrade one weapon.

Fully upgrade two weapons.

Fully upgrade three weapons.

Fully upgrade four weapons.

Fully upgrade five weapons.

Acquire all upgrades for all weapons.

Fully research the Thuggish Splicer.

Fully research the Leadhead Splicer.

Fully research the Spider Splicer.

Fully research the Houdini Splicer.

Fully research the Nitro Splicer.

Fully research the Rosie.

Fully research the Bouncer.

Fully research the Little Sister.

Take at least one photo in every research group.

Max out all possible research.

Take a Research Photo of the highest grade.

Take at least one Research Photo of a Splicer.

Perform at least one successful hack.

Successfully hack a security bot.

Successfully hack a security camera.

Successfully hack a turret.

Successfully hack a vending machine.

Successfully hack a safe.

Successfully complete 50 hacks.

Successfully invent at least one item.

Successfully invent at least 100 items.

Successfully invented all possible ammo types.

Complete the game without harvesting any Little Sisters.

Collect or Invent 53 Tonics in the Physical, Engineering, and Combat tracks.

Find every audio diary.

Complete the game on the hardest difficulty setting.

Either Harvest or Rescue every Little Sister in the game.

Hit the jackpot at a slot machine.

Shock an enemy in the water.

The player has defeated the crazed Dr. Steinman.

The player has defeated Peach Wilkins.

The player has restored the forests of Arcadia.

The player has completed Sander Cohen's great masterpiece.

The player has defeated Andrew Ryan.

The player has broken Fontaine's mind control.

The player has defeated Atlas.

The player has become a Big Daddy.

The player has taken a picture of Sander Cohen's corpse.

The player has entered Sander Cohen's personal quarters.

Complete the game on Hard without using a Vita-Chamber.